Research Groups

 

Publications of Xinlai Cheng (Results: 114)

 

Iminothioindoxyl Donors with Exceptionally High Cross Section for Protein Vibrational Energy Transfer.
Angewandte Chemie (International ed. in English)
Feid C, Luma L, Fischer T, Löffler JG, Grebenovsky N, Wachtveitl J, Heckel A, Bredenbeck J PubMed
Feb 2024 Volume: 63 Issue: 9 Pages: e202317047

A Blue Light and Two-Photon Activatable Rhodamine Fluorophore.
Chemistry (Weinheim an der Bergstrasse, Germany)
Weber R, Junek S, Heckel A PubMed
Jul 2023 Volume: 29 Issue: 38 Pages: e202300997

Extending the Palette of Green Coumarin Photocages - Oligonucleotide Fragmentation and Superior 5'-Caps.
Chemistry (Weinheim an der Bergstrasse, Germany)
Kaufmann J, Wolf J, Heckel A PubMed
May 2023 Volume: 29 Issue: 30 Pages: e202300390

Choose your leaving group: selective photodeprotection in a mixture of HP-caged compounds by VIPER excitation.
Chemical science
van Wilderen LJGW, Kern-Michler D, Neumann C, Reinfelds M, von Cosel J, Horz M, Burghardt I, Heckel A, Bredenbeck J PubMed
Mar 2023 Volume: 14 Issue: 10 Pages: 2624-2630

Rhodamine-Sensitized Two-Photon Activation of a Red Light-Absorbing BODIPY Photocage.
Chemistry (Weinheim an der Bergstrasse, Germany)
Weber R, Chok K, Junek S, Glaubitz C, Heckel A PubMed
May 2023 Volume: 29 Issue: 25 Pages: e202300149

Chromatic Selectivity of Coumarin-Caged Oligonucleotides.
Chemistry (Weinheim an der Bergstrasse, Germany)
Kaufmann J, Sinsel F, Heckel A PubMed
Mar 2023 Volume: 29 Issue: 17 Pages: e202204014

RNA Probes for Visualization of Sarcin/ricin Loop Depurination without Background Fluorescence.
Chemistry, an Asian journal
Klimek R, Kaiser C, Murmann NS, Kaltenschnee N, Spanò T, Wachtveitl J, Schuman EM, Heckel A PubMed
Dec 2022 Volume: 17 Issue: 24 Pages: e202201077

Inactivation of Competitive Decay Channels Leads to Enhanced Coumarin Photochemistry.
Chemistry (Weinheim an der Bergstrasse, Germany)
Klimek R, Asido M, Hermanns V, Junek S, Wachtveitl J, Heckel A PubMed
Jun 2022 Volume: 28 Issue: 35 Pages: e202200647

Green-Light Activatable BODIPY and Coumarin 5'-Caps for Oligonucleotide Photocaging.
Chemistry (Weinheim an der Bergstrasse, Germany)
Kaufmann J, Müller P, Andreadou E, Heckel A PubMed
Jun 2022 Volume: 28 Issue: 36 Pages: e202200477

A long-lived fluorenyl cation: efficiency booster for uncaging and photobase properties.
Physical chemistry chemical physics : PCCP
Abdellaoui C, Hermanns V, Reinfelds M, Scheurer M, Dreuw A, Heckel A, Wachtveitl J PubMed
Mar 2022 Volume: 24 Issue: 9 Pages: 5294-5300

Ultrafast and efficient energy transfer in a one- and two-photon sensitized rhodamine-BODIPY dyad: a perspective for broadly absorbing photocages.
Physical chemistry chemical physics : PCCP
Asido M, Hamerla C, Weber R, Horz M, Niraghatam MS, Heckel A, Burghardt I, Wachtveitl J PubMed
Jan 2022 Volume: 24 Issue: 3 Pages: 1795-1802

Visible light-activatable Q-dye molecular beacons for long-term mRNA monitoring in neurons.
Chemical communications (Cambridge, England)
Klimek R, Donlin-Asp PG, Polisseni C, Hanff V, Schuman EM, Heckel A PubMed
Nov 2021 Volume: 57 Issue: 94 Pages: 12683-12686

Solid-Phase-Supported Chemoenzymatic Synthesis of a Light-Activatable tRNA Derivative.
Angewandte Chemie (International ed. in English)
Blümler A, Schwalbe H, Heckel A PubMed
Jan 2022 Volume: 61 Issue: 1 Pages: e202111613

The RNA chaperone StpA enables fast RNA refolding by destabilization of mutually exclusive base pairs within competing secondary structure elements.
Nucleic acids research
Hohmann KF, Blümler A, Heckel A, Fürtig B PubMed
Nov 2021 Volume: 49 Issue: 19 Pages: 11337-11349

Rethinking Uncaging: A New Antiaromatic Photocage Driven by a Gain of Resonance Energy.
Chemistry (Weinheim an der Bergstrasse, Germany)
Hermanns V, Scheurer M, Kersten NF, Abdellaoui C, Wachtveitl J, Dreuw A, Heckel A PubMed
Oct 2021 Volume: 27 Issue: 56 Pages: 14121-14127

Controlling Coagulation in Blood with Red Light.
Angewandte Chemie (International ed. in English)
Müller P, Sahlbach M, Gasper S, Mayer G, Müller J, Pötzsch B, Heckel A PubMed
Oct 2021 Volume: 60 Issue: 41 Pages: 22441-22446

Light-Induced Quantitative and Electrical-Field-Induced Barrierless Switching of Spiropyran Derivative on Graphite Surface.
The journal of physical chemistry letters
Malik H, Halbritter T, Heckel A, Gopakumar TG PubMed
Jun 2021 Volume: 12 Issue: 23 Pages: 5463-5468

Proton-Transfer Dynamics of Photoacidic Merocyanines in Aqueous Solution.
Chemistry (Weinheim an der Bergstrasse, Germany)
Kaiser C, Halbritter T, Heckel A, Wachtveitl J PubMed
Jun 2021 Volume: 27 Issue: 35 Pages: 9160-9173

Unraveling the Kinetics of Spare-Tire DNA G-Quadruplex Folding.
Journal of the American Chemical Society
Grün JT, Blümler A, Burkhart I, Wirmer-Bartoschek J, Heckel A, Schwalbe H PubMed
Apr 2021 Volume: 143 Issue: 16 Pages: 6185-6193

Differential regulation of local mRNA dynamics and translation following long-term potentiation and depression.
Proceedings of the National Academy of Sciences of the United States of America
Donlin-Asp PG, Polisseni C, Klimek R, Heckel A, Schuman EM PubMed
Mar 2021 Volume: 118 Issue: 13 Pages:

Parallel reaction pathways accelerate folding of a guanine quadruplex.
Nucleic acids research
Harkness RW, Hennecker C, Grün JT, Blümler A, Heckel A, Schwalbe H, Mittermaier AK PubMed
Feb 2021 Volume: 49 Issue: 3 Pages: 1247-1262

Photo-tethered molecular beacons for superior light-induction.
Chemical communications (Cambridge, England)
Klimek R, Wang M, McKenney VR, Schuman EM, Heckel A PubMed
Jan 2021 Volume: 57 Issue: 5 Pages: 615-618

Selective Modification for Red-Shifted Excitability: A Small Change in Structure, a Huge Change in Photochemistry.
Chemistry (Weinheim an der Bergstrasse, Germany)
Becker Y, Roth S, Scheurer M, Jakob A, Gacek DA, Walla PJ, Dreuw A, Wachtveitl J, Heckel A PubMed
Jan 2021 Volume: 27 Issue: 6 Pages: 2212-2218

Light-Induced Uncaging for Time-Resolved Observations of Biochemical Reactions by MAS NMR Spectroscopy.
Chemistry (Weinheim an der Bergstrasse, Germany)
de Mos J, Jakob A, Becker-Baldus J, Heckel A, Glaubitz C PubMed
May 2020 Volume: 26 Issue: 30 Pages: 6789-6792

Refolding through a Linear Transition State Enables Fast Temperature Adaptation of a Translational Riboswitch.
Biochemistry
Fürtig B, Oberhauser EM, Zetzsche H, Klötzner DP, Heckel A, Schwalbe H PubMed
Mar 2020 Volume: 59 Issue: 10 Pages: 1081-1086

Conformational Dynamics of Strand Register Shifts in DNA G-Quadruplexes.
Journal of the American Chemical Society
Grün JT, Hennecker C, Klötzner DP, Harkness RW, Bessi I, Heckel A, Mittermaier AK, Schwalbe H PubMed
Jan 2020 Volume: 142 Issue: 1 Pages: 264-273

Introducing LNAzo: More Rigidity for Improved Photocontrol of Oligonucleotide Hybridization.
Chemistry (Weinheim an der Bergstrasse, Germany)
Grebenovsky N, Luma L, Müller P, Heckel A PubMed
Sep 2019 Volume: 25 Issue: 53 Pages: 12298-12302

Phosphodiester photo-tethers for the (multi-)cyclic conformational caging of oligonucleotides.
Methods in enzymology
Müller P, Seyfried P, Frühauf A, Heckel A PubMed
2019 Volume: 624 Issue: Pages: 89-111

Global response of diacylglycerol kinase towards substrate binding observed by 2D and 3D MAS NMR.
Scientific reports
Möbius K, Kazemi S, Güntert P, Jakob A, Heckel A, Becker-Baldus J, Glaubitz C PubMed
Mar 2019 Volume: 9 Issue: 1 Pages: 3995

A light-responsive RNA aptamer for an azobenzene derivative.
Nucleic acids research
Lotz TS, Halbritter T, Kaiser C, Rudolph MM, Kraus L, Groher F, Steinwand S, Wachtveitl J, Heckel A, Suess B PubMed
Feb 2019 Volume: 47 Issue: 4 Pages: 2029-2040

"End-to-end" stacking of small dsRNA.
RNA (New York, N.Y.)
Erlenbach N, Grünewald C, Krstic B, Heckel A, Prisner TF PubMed
Feb 2019 Volume: 25 Issue: 2 Pages: 239-246

Low-Threshold Reversible Electron-Induced and Selective Photoinduced Switching of Azobenzene Derivatives under Ambient Conditions.
The journal of physical chemistry letters
Yadav K, Mahapatra S, Halbritter T, Heckel A, Gopakumar TG PubMed
Nov 2018 Volume: 9 Issue: 21 Pages: 6326-6333

Optimal Destabilization of DNA Double Strands by Single-Nucleobase Caging.
Chemistry (Weinheim an der Bergstrasse, Germany)
Seyfried P, Heinz M, Pintér G, Klötzner DP, Becker Y, Bolte M, Jonker HRA, Stelzl LS, Hummer G, Schwalbe H, Heckel A PubMed
Nov 2018 Volume: 24 Issue: 66 Pages: 17568-17576

Chemo-Enzymatic Synthesis of Position-Specifically Modified RNA for Biophysical Studies including Light Control and NMR Spectroscopy.
Angewandte Chemie (International ed. in English)
Keyhani S, Goldau T, Blümler A, Heckel A, Schwalbe H PubMed
Sep 2018 Volume: 57 Issue: 37 Pages: 12017-12021

A New Photocage Derived from Fluorene.
Chemistry (Weinheim an der Bergstrasse, Germany)
Reinfelds M, von Cosel J, Falahati K, Hamerla C, Slanina T, Burghardt I, Heckel A PubMed
Sep 2018 Volume: 24 Issue: 49 Pages: 13026-13035

A red-shifted two-photon-only caging group for three-dimensional photorelease.
Chemical science
Becker Y, Unger E, Fichte MAH, Gacek DA, Dreuw A, Wachtveitl J, Walla PJ, Heckel A PubMed
Mar 2018 Volume: 9 Issue: 10 Pages: 2797-2802

Life times of metastable states guide regulatory signaling in transcriptional riboswitches.
Nature communications
Helmling C, Klötzner DP, Sochor F, Mooney RA, Wacker A, Landick R, Fürtig B, Heckel A, Schwalbe H PubMed
Mar 2018 Volume: 9 Issue: 1 Pages: 944

Sensitized Two-Photon Activation of Coumarin Photocages.
The journal of physical chemistry letters
Hammer CA, Falahati K, Jakob A, Klimek R, Burghardt I, Heckel A, Wachtveitl J PubMed
Mar 2018 Volume: 9 Issue: 6 Pages: 1448-1453

Light Regulation of DNA Minicircle Dimerization by Utilizing Azobenzene C-Nucleosides.
Chemistry (Weinheim an der Bergstrasse, Germany)
Grebenovsky N, Goldau T, Bolte M, Heckel A PubMed
Mar 2018 Volume: 24 Issue: 14 Pages: 3425-3428

Controlling Photochemistry via Isotopomers and IR Pre-excitation.
Journal of the American Chemical Society
Kern-Michler D, Neumann C, Mielke N, van Wilderen LJGW, Reinfelds M, von Cosel J, Santoro F, Heckel A, Burghardt I, Bredenbeck J PubMed
Jan 2018 Volume: 140 Issue: 3 Pages: 926-931

A new photoactivatable near-infrared-emitting QCy7 fluorophore for single-molecule super-resolution microscopy.
Chemical communications (Cambridge, England)
Klötzner DP, Klehs K, Heilemann M, Heckel A PubMed
Aug 2017 Volume: 53 Issue: 71 Pages: 9874-9877

Pyridine-Spiropyran Derivative as a Persistent, Reversible Photoacid in Water.
The Journal of organic chemistry
Halbritter T, Kaiser C, Wachtveitl J, Heckel A PubMed
Aug 2017 Volume: 82 Issue: 15 Pages: 8040-8047

A Two-Photon-Photocleavable Linker for Triggering Light-Induced Strand Breaks in Oligonucleotides.
ACS chemical biology
Weyel XMM, Fichte MAH, Heckel A PubMed
Aug 2017 Volume: 12 Issue: 8 Pages: 2183-2190

Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice.
Nature communications
Lucas T, Schäfer F, Müller P, Eming SA, Heckel A, Dimmeler S PubMed
May 2017 Volume: 8 Issue: Pages: 15162

Lanthanide Ions Coupled with Photoinduced Electron Transfer Generate Strong Reduction Potentials from Visible Light.
Chemistry (Weinheim an der Bergstrasse, Germany)
Meyer AU, Slanina T, Heckel A, König B PubMed
Jun 2017 Volume: 23 Issue: 33 Pages: 7900-7904

Activity-dependent spatially localized miRNA maturation in neuronal dendrites.
Science (New York, N.Y.)
Sambandan S, Akbalik G, Kochen L, Rinne J, Kahlstatt J, Glock C, Tushev G, Alvarez-Castelao B, Heckel A, Schuman EM PubMed
Feb 2017 Volume: 355 Issue: 6325 Pages: 634-637

Photo-Tethers for the (Multi-)Cyclic, Conformational Caging of Long Oligonucleotides.
Angewandte Chemie (International ed. in English)
Seyfried P, Eiden L, Grebenovsky N, Mayer G, Heckel A PubMed
Jan 2017 Volume: 56 Issue: 1 Pages: 359-363

Three-Dimensional Control of DNA Hybridization by Orthogonal Two-Color Two-Photon Uncaging.
Angewandte Chemie (International ed. in English)
Fichte MA, Weyel XM, Junek S, Schäfer F, Herbivo C, Goeldner M, Specht A, Wachtveitl J, Heckel A PubMed
Jul 2016 Volume: 55 Issue: 31 Pages: 8948-52

Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif.
Angewandte Chemie (International ed. in English)
Thevarpadam J, Bessi I, Binas O, Gonçalves DP, Slavov C, Jonker HR, Richter C, Wachtveitl J, Schwalbe H, Heckel A PubMed
Feb 2016 Volume: 55 Issue: 8 Pages: 2738-42

Sensitive detection of cancer cells using light-mediated apta-PCR.
Methods (San Diego, Calif.)
Civit L, Pinto A, Rodrigues-Correia A, Heckel A, O'Sullivan CK, Mayer G PubMed
Mar 2016 Volume: 97 Issue: Pages: 104-9

Azobenzene C-Nucleosides for Photocontrolled Hybridization of DNA at Room Temperature.
Chemistry (Weinheim an der Bergstrasse, Germany)
Goldau T, Murayama K, Brieke C, Asanuma H, Heckel A PubMed
Dec 2015 Volume: 21 Issue: 49 Pages: 17870-6

Caged Fluoride: Photochemistry and Applications of 4-Hydroxyphenacyl Fluoride.
Organic letters
Slanina T, Šebej P, Heckel A, Givens RS, Klán P PubMed
Oct 2015 Volume: 17 Issue: 19 Pages: 4814-7

Ultrafast Spectroscopy of Hydroxy-Substituted Azobenzenes in Water.
Chemistry (Weinheim an der Bergstrasse, Germany)
Steinwand S, Halbritter T, Rastädter D, Ortiz-Sánchez JM, Burghardt I, Heckel A, Wachtveitl J PubMed
Oct 2015 Volume: 21 Issue: 44 Pages: 15720-31

A two-photon activatable amino acid linker for the induction of fluorescence.
Chemical communications (Cambridge, England)
Friedrich F, Klehs K, Fichte MA, Junek S, Heilemann M, Heckel A PubMed
Oct 2015 Volume: 51 Issue: 84 Pages: 15382-5

In Search of an Efficient Photoswitch for Functional RNA: Design Principles from a Microscopic Analysis of Azobenzene-linker-RNA Dynamics with Different Linkers.
The journal of physical chemistry. B
Mondal P, Biswas M, Goldau T, Heckel A, Burghardt I PubMed
Aug 2015 Volume: 119 Issue: 34 Pages: 11275-86

Water-soluble Py-BIPS spiropyrans as photoswitches for biological applications.
Organic letters
Özçoban C, Halbritter T, Steinwand S, Herzig LM, Kohl-Landgraf J, Askari N, Groher F, Fürtig B, Richter C, Schwalbe H, Suess B, Wachtveitl J, Heckel A PubMed
Mar 2015 Volume: 17 Issue: 6 Pages: 1517-20

Characterization of conformational dynamics of bistable RNA by equilibrium and non-equilibrium NMR.
Current protocols in nucleic acid chemistry
Fürtig B, Reining A, Sochor F, Oberhauser EM, Heckel A, Schwalbe H PubMed
Dec 2014 Volume: 55 Issue: Pages: 11.13.1-16

Click chemistry facilitates direct labelling and super-resolution imaging of nucleic acids and proteins†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4ra01027bClick here for additional data file.
RSC advances
Raulf A, Spahn CK, Zessin PJ, Finan K, Bernhardt S, Heckel A, Heilemann M PubMed
Jul 2014 Volume: 4 Issue: 57 Pages: 30462-30466

Reversible photoswitching of RNA hybridization at room temperature with an azobenzene C-nucleoside.
Chemistry (Weinheim an der Bergstrasse, Germany)
Goldau T, Murayama K, Brieke C, Steinwand S, Mondal P, Biswas M, Burghardt I, Wachtveitl J, Asanuma H, Heckel A PubMed
Feb 2015 Volume: 21 Issue: 7 Pages: 2845-54

Direct observation of mobility state transitions in RNA trajectories by sensitive single molecule feedback tracking.
Nucleic acids research
Spille JH, Kaminski TP, Scherer K, Rinne JS, Heckel A, Kubitscheck U PubMed
Jan 2015 Volume: 43 Issue: 2 Pages: e14

Selective uncaging of DNA through reaction rate selectivity.
Organic letters
Rodrigues-Correia A, Knapp-Bühle D, Engels JW, Heckel A PubMed
Oct 2014 Volume: 16 Issue: 19 Pages: 5128-31

Wavelength-selective uncaging of oligonucleotides.
Current protocols in nucleic acid chemistry
Rodrigues-Correia A, Seyfried P, Heckel A PubMed
Jun 2014 Volume: 57 Issue: Pages: 6.11.1-32

Three-dimensional protein networks assembled by two-photon activation.
Angewandte Chemie (International ed. in English)
Gatterdam V, Ramadass R, Stoess T, Fichte MA, Wachtveitl J, Heckel A, Tampé R PubMed
May 2014 Volume: 53 Issue: 22 Pages: 5680-4

Influence of the absolute configuration of npe-caged cytosine on DNA single base pair stability.
Angewandte Chemie (International ed. in English)
Steinert HS, Schäfer F, Jonker HR, Heckel A, Schwalbe H PubMed
Jan 2014 Volume: 53 Issue: 4 Pages: 1072-5

Regulating angiogenesis with light-inducible AntimiRs.
Angewandte Chemie (International ed. in English)
Schäfer F, Wagner J, Knau A, Dimmeler S, Heckel A PubMed
Dec 2013 Volume: 52 Issue: 51 Pages: 13558-61

Aptamer-guided caging for selective masking of protein domains.
Angewandte Chemie (International ed. in English)
Rohrbach F, Schäfer F, Fichte MA, Pfeiffer F, Müller J, Pötzsch B, Heckel A, Mayer G PubMed
Nov 2013 Volume: 52 Issue: 45 Pages: 11912-5

Spiropyran photoswitches in the context of DNA: synthesis and photochromic properties.
Chemistry (Weinheim an der Bergstrasse, Germany)
Brieke C, Heckel A PubMed
Nov 2013 Volume: 19 Issue: 46 Pages: 15726-34

Four levels of wavelength-selective uncaging for oligonucleotides.
Organic letters
Rodrigues-Correia A, Weyel XM, Heckel A PubMed
Nov 2013 Volume: 15 Issue: 21 Pages: 5500-3

Light-inducible molecular beacons for spatio-temporally highly defined activation.
Chemical communications (Cambridge, England)
Rinne JS, Kaminski TP, Kubitscheck U, Heckel A PubMed
Jun 2013 Volume: 49 Issue: 47 Pages: 5375-7

Light-controlled tools.
Angewandte Chemie (International ed. in English)
Brieke C, Rohrbach F, Gottschalk A, Mayer G, Heckel A PubMed
Aug 2012 Volume: 51 Issue: 34 Pages: 8446-76

Ultrafast dynamics of a spiropyran in water.
Journal of the American Chemical Society
Kohl-Landgraf J, Braun M, Özçoban C, Gonçalves DP, Heckel A, Wachtveitl J PubMed
Aug 2012 Volume: 134 Issue: 34 Pages: 14070-7

Computational design of improved two-photon active caging compounds based on nitrodibenzofuran.
Journal of computational chemistry
Dreuw A, Polkehn MA, Binder R, Heckel A, Knippenberg S PubMed
Aug 2012 Volume: 33 Issue: 22 Pages: 1797-805

Caged glutathione - triggering protein interaction by light.
Angewandte Chemie (International ed. in English)
Gatterdam V, Stoess T, Menge C, Heckel A, Tampé R PubMed
Apr 2012 Volume: 51 Issue: 16 Pages: 3960-3

Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs.
RNA (New York, N.Y.)
Wurm JP, Griese M, Bahr U, Held M, Heckel A, Karas M, Soppa J, Wöhnert J PubMed
Mar 2012 Volume: 18 Issue: 3 Pages: 412-20

Light-activatable molecular beacons with a caged loop sequence.
Chemical communications (Cambridge, England)
Joshi KB, Vlachos A, Mikat V, Deller T, Heckel A PubMed
Mar 2012 Volume: 48 Issue: 22 Pages: 2746-8

Functional detection of proteins by caged aptamers.
ACS chemical biology
Pinto A, Lennarz S, Rodrigues-Correia A, Heckel A, O'Sullivan CK, Mayer G PubMed
Feb 2012 Volume: 7 Issue: 2 Pages: 360-6

Caged glucosamine-6-phosphate for the light-control of riboswitch activity.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Wulffen B, Buff MC, Pofahl M, Mayer G, Heckel A PubMed
Mar 2012 Volume: 11 Issue: 3 Pages: 489-92

Coumarin-caged dG for improved wavelength-selective uncaging of DNA.
Organic letters
Menge C, Heckel A PubMed
Sep 2011 Volume: 13 Issue: 17 Pages: 4620-3

A light trigger for DNA nanotechnology.
Small (Weinheim an der Bergstrasse, Germany)
Schmidt TL, Koeppel MB, Thevarpadam J, Gonçalves DP, Heckel A PubMed
Aug 2011 Volume: 7 Issue: 15 Pages: 2163-7

Photon cascade with clip-on fluorophores.
Chemphyschem : a European journal of chemical physics and physical chemistry
Friedrich F, Heckel A PubMed
Aug 2011 Volume: 12 Issue: 11 Pages: 2073-5

Construction of a structurally defined double-stranded DNA catenane.
Nano letters
Schmidt TL, Heckel A PubMed
Apr 2011 Volume: 11 Issue: 4 Pages: 1739-42

Wavelength-selective uncaging of dA and dC residues.
Organic letters
Schäfer F, Joshi KB, Fichte MA, Mack T, Wachtveitl J, Heckel A PubMed
Mar 2011 Volume: 13 Issue: 6 Pages: 1450-3

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.
Nucleic acids research
Meyer B, Wurm JP, Kötter P, Leisegang MS, Schilling V, Buchhaupt M, Held M, Bahr U, Karas M, Heckel A, Bohnsack MT, Wöhnert J, Entian KD PubMed
Mar 2011 Volume: 39 Issue: 4 Pages: 1526-37

Comparison of the duplex-destabilizing effects of nucleobase-caged oligonucleotides.
Analytical and bioanalytical chemistry
Rodrigues-Correia A, Koeppel MB, Schäfer F, Joshi KB, Mack T, Heckel A PubMed
Jan 2011 Volume: 399 Issue: 1 Pages: 441-7

DNA minicircles connected via G-quadruplex interaction modules.
Small (Weinheim an der Bergstrasse, Germany)
Gonçalves DP, Schmidt TL, Koeppel MB, Heckel A PubMed
Jun 2010 Volume: 6 Issue: 12 Pages: 1347-52

Assembly of dsDNA nanocircles into dimeric and oligomeric aggregates.
Chemical communications (Cambridge, England)
Ackermann D, Rasched G, Verma S, Schmidt TL, Heckel A, Famulok M PubMed
Jun 2010 Volume: 46 Issue: 23 Pages: 4154-6

Prion protein amyloid formation involves structural rearrangements in the C-terminal domain.
Chembiochem : a European journal of chemical biology
Kumar J, Sreeramulu S, Schmidt TL, Richter C, Vonck J, Heckel A, Glaubitz C, Schwalbe H PubMed
Jun 2010 Volume: 11 Issue: 9 Pages: 1208-13

A double-stranded DNA rotaxane.
Nature nanotechnology
Ackermann D, Schmidt TL, Hannam JS, Purohit CS, Heckel A, Famulok M PubMed
Jun 2010 Volume: 5 Issue: 6 Pages: 436-42

The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase.
Nucleic acids research
Wurm JP, Meyer B, Bahr U, Held M, Frolow O, Kötter P, Engels JW, Heckel A, Karas M, Entian KD, Wöhnert J PubMed
Apr 2010 Volume: 38 Issue: 7 Pages: 2387-98

Dependence of aptamer activity on opposed terminal extensions: improvement of light-regulation efficiency.
Nucleic acids research
Buff MC, Schäfer F, Wulffen B, Müller J, Pötzsch B, Heckel A, Mayer G PubMed
Apr 2010 Volume: 38 Issue: 6 Pages: 2111-8

From selection to caged aptamers: identification of light-dependent ssDNA aptamers targeting cytohesin.
Bioorganic & medicinal chemistry letters
Mayer G, Lohberger A, Butzen S, Pofahl M, Blind M, Heckel A PubMed
Dec 2009 Volume: 19 Issue: 23 Pages: 6561-4

Probing the limits of liquid droplet laser desorption mass spectrometry in the analysis of oligonucleotides and nucleic acids.
Rapid communications in mass spectrometry : RCM
Hoffmann J, Schmidt TL, Heckel A, Brutschy B PubMed
Jul 2009 Volume: 23 Issue: 14 Pages: 2176-80

Pyrrole/imidazole-polyamide anchors for DNA tertiary interactions.
Small (Weinheim an der Bergstrasse, Germany)
Schmidt TL, Heckel A PubMed
Jul 2009 Volume: 5 Issue: 13 Pages: 1517-20

Structure-activity relationships of a caged thrombin binding DNA aptamer: insight gained from molecular dynamics simulation studies.
Journal of structural biology
Jayapal P, Mayer G, Heckel A, Wennmohs F PubMed
Jun 2009 Volume: 166 Issue: 3 Pages: 241-50

Differential regulation of protein subdomain activity with caged bivalent ligands.
Chembiochem : a European journal of chemical biology
Mayer G, Müller J, Mack T, Freitag DF, Höver T, Pötzsch B, Heckel A PubMed
Mar 2009 Volume: 10 Issue: 4 Pages: 654-7

Completion of a Programmable DNA-Binding Small Molecule Library.
Tetrahedron
Hsu CF, Phillips JW, Trauger JW, Farkas ME, Belitsky JM, Heckel A, Olenyuk BZ, Puckett JW, Wang CC, Dervan PB PubMed
Jul 2007 Volume: 63 Issue: 27 Pages: 6146-6151

Nucleobase-caged phosphoramidites for oligonucleotide synthesis.
Current protocols in nucleic acid chemistry
Heckel A PubMed
Jun 2007 Volume: Chapter 1 Issue: Pages: Unit 1.17

Building objects from nucleic acids for a nanometer world.
Biochimie
Heckel A, Famulok M PubMed
Jul 2008 Volume: 90 Issue: 7 Pages: 1096-107

Binding of hairpin polyamides to DNA studied by fluorescence correlation spectroscopy for DNA nanoarchitectures.
Analytical and bioanalytical chemistry
Nandi CK, Parui PP, Schmidt TL, Heckel A, Brutschy B PubMed
Mar 2008 Volume: 390 Issue: 6 Pages: 1595-603

DNA minicircles with gaps for versatile functionalization.
Angewandte Chemie (International ed. in English)
Rasched G, Ackermann D, Schmidt TL, Broekmann P, Heckel A, Famulok M PubMed
2008 Volume: 47 Issue: 5 Pages: 967-70

Light-dependent RNA interference with nucleobase-caged siRNAs.
RNA (New York, N.Y.)
Mikat V, Heckel A PubMed
Dec 2007 Volume: 13 Issue: 12 Pages: 2341-7

Polyamide struts for DNA architectures.
Angewandte Chemie (International ed. in English)
Schmidt TL, Nandi CK, Rasched G, Parui PP, Brutschy B, Famulok M, Heckel A PubMed
2007 Volume: 46 Issue: 23 Pages: 4382-4

Light-stimulated patterning of cells.
Chembiochem : a European journal of chemical biology
Mayer G, Heckel A PubMed
May 2007 Volume: 8 Issue: 8 Pages: 857-8

An anticoagulant with light-triggered antidote activity.
Angewandte Chemie (International ed. in English)
Heckel A, Buff MC, Raddatz MS, Müller J, Pötzsch B, Mayer G PubMed
Oct 2006 Volume: 45 Issue: 40 Pages: 6748-50

Biologically active molecules with a "light switch".
Angewandte Chemie (International ed. in English)
Mayer G, Heckel A PubMed
Jul 2006 Volume: 45 Issue: 30 Pages: 4900-21

Light-induced formation of G-quadruplex DNA secondary structures.
Chembiochem : a European journal of chemical biology
Mayer G, Kröck L, Mikat V, Engeser M, Heckel A PubMed
Nov 2005 Volume: 6 Issue: 11 Pages: 1966-70

A ribozyme for the aldol reaction.
Chemistry & biology
Fusz S, Eisenführ A, Srivatsan SG, Heckel A, Famulok M PubMed
Aug 2005 Volume: 12 Issue: 8 Pages: 941-50

Light regulation of aptamer activity: an anti-thrombin aptamer with caged thymidine nucleobases.
Journal of the American Chemical Society
Heckel A, Mayer G PubMed
Jan 2005 Volume: 127 Issue: 3 Pages: 822-3

Photoinduced transcription by using temporarily mismatched caged oligonucleotides.
Angewandte Chemie (International ed. in English)
Kröck L, Heckel A PubMed
Jan 2005 Volume: 44 Issue: 3 Pages: 471-3

A new DNA analogue with expanded size and scope.
Chembiochem : a European journal of chemical biology
Heckel A PubMed
Jun 2004 Volume: 5 Issue: 6 Pages: 765-7

Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates.
Nucleic acids research
Edelson BS, Best TP, Olenyuk B, Nickols NG, Doss RM, Foister S, Heckel A, Dervan PB PubMed
2004 Volume: 32 Issue: 9 Pages: 2802-18

U-pin polyamide motif for recognition of the DNA minor groove.
Chemistry (Weinheim an der Bergstrasse, Germany)
Heckel A, Dervan PB PubMed
Jul 2003 Volume: 9 Issue: 14 Pages: 3353-66

Preparation and characterization of TADDOLs immobilized on hydrophobic controlled-pore-glass silica gel and their use in enantioselective heterogeneous catalysis.
Chemistry (Weinheim an der Bergstrasse, Germany)
Heckel A, Seebach D PubMed
Feb 2002 Volume: 8 Issue: 3 Pages: 559-72

TADDOLs, Their Derivatives, and TADDOL Analogues: Versatile Chiral Auxiliaries.
Angewandte Chemie (International ed. in English)
Seebach D, Beck AK, Heckel A PubMed
Jan 2001 Volume: 40 Issue: 1 Pages: 92-138