Research Groups

 

Publications of ?author=Ivan Dikic (Results: 76)

 

Targeted protein degradation via intramolecular bivalent glues.
Nature
Hsia O, Hinterndorfer M, Cowan AD, Iso K, Ishida T, Sundaramoorthy R, Nakasone MA, Imrichova H, Schätz C, Rukavina A, Husnjak K, Wegner M, Correa-Sáez A, Craigon C, Casement R, Maniaci C, Testa A, Kaulich M, Dikic I, Winter GE, Ciulli A PubMed
Mar 2024 Volume: 627 Issue: 8002 Pages: 204-211

Atg8 family proteins, LIR/AIM motifs and other interaction modes.
Autophagy reports
Rogov VV, Nezis IP, Tsapras P, Zhang H, Dagdas Y, Noda NN, Nakatogawa H, Wirth M, Mouilleron S, McEwan DG, Behrends C, Deretic V, Elazar Z, Tooze SA, Dikic I, Lamark T, Johansen T PubMed
Dec 2023 Volume: 2 Issue: 1 Pages:

An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant.
Cell reports
Mende H, Khatri A, Lange C, Poveda-Cuevas SA, Tascher G, Covarrubias-Pinto A, Löhr F, Koschade SE, Dikic I, Münch C, Bremm A, Brunetti L, Brandts CH, Uckelmann H, Dötsch V, Rogov VV, Bhaskara RM, Müller S PubMed
Dec 2023 Volume: 42 Issue: 12 Pages: 113484

Mechanism and evolutionary origins of alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10.
Cell reports
Patil PR, Burroughs AM, Misra M, Cerullo F, Costas-Insua C, Hung HC, Dikic I, Aravind L, Joazeiro CAP PubMed
Sep 2023 Volume: 42 Issue: 9 Pages: 113100

Ubiquitination and cell-autonomous immunity.
Current opinion in immunology
Mello-Vieira J, Bopp T, Dikic I PubMed
Oct 2023 Volume: 84 Issue: Pages: 102368

The mission to ensure continued funding for excellent basic research.
EMBO reports
Lamond AI, Dikic I, Nussenzweig A, Müller CW, Thornton JM, Yaffe MB PubMed
Jul 2023 Volume: 24 Issue: 7 Pages: e57498

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.
Nature
González A, Covarrubias-Pinto A, Bhaskara RM, Glogger M, Kuncha SK, Xavier A, Seemann E, Misra M, Hoffmann ME, Bräuning B, Balakrishnan A, Qualmann B, Dötsch V, Schulman BA, Kessels MM, Hübner CA, Heilemann M, Hummer G, Dikić I PubMed
Jun 2023 Volume: 618 Issue: 7964 Pages: 394-401

Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.
Nature
Foronda H, Fu Y, Covarrubias-Pinto A, Bocker HT, González A, Seemann E, Franzka P, Bock A, Bhaskara RM, Liebmann L, Hoffmann ME, Katona I, Koch N, Weis J, Kurth I, Gleeson JG, Reggiori F, Hummer G, Kessels MM, Qualmann B, Mari M, Dikić I, Hübner CA PubMed
Jun 2023 Volume: 618 Issue: 7964 Pages: 402-410

Mycobacterium tuberculosis hijacks ubiquitin to inhibit pyroptosis.
Molecular cell
Krause DS, Dikic I PubMed
Dec 2022 Volume: 82 Issue: 24 Pages: 4588-4590

USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction.
Cell reports
Hertel A, Alves LM, Dutz H, Tascher G, Bonn F, Kaulich M, Dikic I, Eimer S, Steinberg F, Bremm A PubMed
Dec 2022 Volume: 41 Issue: 10 Pages: 111653

A20 binding and inhibitor of nuclear factor kappa B (NF-κB)-1 (ABIN-1): a novel modulator of mitochondrial autophagy.
American journal of physiology. Cell physiology
Merline R, Rödig H, Zeng-Brouwers J, Poluzzi C, Tascher G, Michaelis J, Lopez-Mosqueda J, Rhiner A, Huber LS, Diehl V, Dikic I, Kögel D, Münch C, Wygrecka M, Schaefer L PubMed
Feb 2023 Volume: 324 Issue: 2 Pages: C339-C352

Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2.
Cell reports
Oo JA, Pálfi K, Warwick T, Wittig I, Prieto-Garcia C, Matkovic V, Tomašković I, Boos F, Izquierdo Ponce J, Teichmann T, Petriukov K, Haydar S, Maegdefessel L, Wu Z, Pham MD, Krishnan J, Baker AH, Günther S, Ulrich HD, Dikic I, Leisegang MS, Brandes RP PubMed
Nov 2022 Volume: 41 Issue: 7 Pages: 111670

Arginine ADP-Ribosylation: Chemical Synthesis of Post-Translationally Modified Ubiquitin Proteins.
Journal of the American Chemical Society
Voorneveld J, Kloet MS, Wijngaarden S, Kim RQ, Moutsiopoulou A, Verdegaal M, Misra M, Đikić I, van der Marel GA, Overkleeft HS, Filippov DV, van der Heden van Noort GJ PubMed
Nov 2022 Volume: 144 Issue: 45 Pages: 20582-20589

An expanded lexicon for the ubiquitin code.
Nature reviews. Molecular cell biology
Dikic I, Schulman BA PubMed
Apr 2023 Volume: 24 Issue: 4 Pages: 273-287

Localization matters in targeted protein degradation.
Cell chemical biology
Shah VJ, Đikić I PubMed
Oct 2022 Volume: 29 Issue: 10 Pages: 1465-1466

Impact of mesenchymal stromal cell-derived vesicular cargo on B-cell acute lymphoblastic leukemia progression.
Blood advances
Karantanou C, Minciacchi VR, Kumar R, Zanetti C, Bravo J, Pereira RS, Tascher G, Tertel T, Covarrubias-Pinto A, Bankov K, Pfeffermann LM, Bonig H, Divieti-Pajevic P, McEwan DG, Giebel B, Münch C, Dikic I, Krause DS PubMed
Apr 2023 Volume: 7 Issue: 7 Pages: 1190-1203

Mathematical modeling of the molecular switch of TNFR1-mediated signaling pathways applying Petri net formalism and in silico knockout analysis.
PLoS computational biology
Amstein LK, Ackermann J, Hannig J, Đikić I, Fulda S, Koch I PubMed
Aug 2022 Volume: 18 Issue: 8 Pages: e1010383

Secretes a Bioactive Lipid That Triggers Inflammatory Signaling and Cell Death.
Frontiers in microbiology
Tiku V, Kew C, Kofoed EM, Peng Y, Dikic I, Tan MW PubMed
2022 Volume: 13 Issue: Pages: 870101

USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K.
Molecular oncology
Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Bozkurt S, Pahor N, Fuss C, Schirbel A, Schülein-Völk C, Buchberger A, Calzado Canale MA, Rosenfeldt M, Dikic I, Münch C, Diefenbacher ME PubMed
Sep 2022 Volume: 16 Issue: 17 Pages: 3082-3106

Ubiquitin and Legionella: From bench to bedside.
Seminars in cell & developmental biology
Tomaskovic I, Gonzalez A, Dikic I PubMed
Dec 2022 Volume: 132 Issue: Pages: 230-241

USP28: Oncogene or Tumor Suppressor? A Unifying Paradigm for Squamous Cell Carcinoma.
Cells
Prieto-Garcia C, Tomašković I, Shah VJ, Dikic I, Diefenbacher M PubMed
Oct 2021 Volume: 10 Issue: 10 Pages:

OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice.
Nature communications
Schünke H, Göbel U, Dikic I, Pasparakis M PubMed
Oct 2021 Volume: 12 Issue: 1 Pages: 5912

Inhibition of USP28 overcomes Cisplatin-resistance of squamous tumors by suppression of the Fanconi anemia pathway.
Cell death and differentiation
Prieto-Garcia C, Hartmann O, Reissland M, Fischer T, Maier CR, Rosenfeldt M, Schülein-Völk C, Klann K, Kalb R, Dikic I, Münch C, Diefenbacher ME PubMed
Mar 2022 Volume: 29 Issue: 3 Pages: 568-584

Autophagy in major human diseases.
The EMBO journal
Klionsky DJ, Petroni G, Amaravadi RK, Baehrecke EH, Ballabio A, Boya P, Bravo-San Pedro JM, Cadwell K, Cecconi F, Choi AMK, Choi ME, Chu CT, Codogno P, Colombo MI, Cuervo AM, Deretic V, Dikic I, Elazar Z, Eskelinen EL, Fimia GM, Gewirtz DA, Green DR, Hansen M, Jäättelä M, Johansen T, Juhász G, Karantza V, Kraft C, Kroemer G, Ktistakis NT, Kumar S, Lopez-Otin C, Macleod KF, Madeo F, Martinez J, Meléndez A, Mizushima N, Münz C, Penninger JM, Perera RM, Piacentini M, Reggiori F, Rubinsztein D... PubMed
Oct 2021 Volume: 40 Issue: 19 Pages: e108863

Calcitriol Promotes Differentiation of Glioma Stem-Like Cells and Increases Their Susceptibility to Temozolomide.
Cancers
Gerstmeier J, Possmayer AL, Bozkurt S, Hoffmann ME, Dikic I, Herold-Mende C, Burger MC, Münch C, Kögel D, Linder B PubMed
Jul 2021 Volume: 13 Issue: 14 Pages:

Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection.
Cell death and differentiation
Liu Y, Mukherjee R, Bonn F, Colby T, Matic I, Glogger M, Heilemann M, Dikic I PubMed
Oct 2021 Volume: 28 Issue: 10 Pages: 2957-2969

Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.
PloS one
Armstrong LA, Lange SM, Dee Cesare V, Matthews SP, Nirujogi RS, Cole I, Hope A, Cunningham F, Toth R, Mukherjee R, Bojkova D, Gruber F, Gray D, Wyatt PG, Cinatl J, Dikic I, Davies P, Kulathu Y PubMed
2021 Volume: 16 Issue: 7 Pages: e0253364

Autophagy: Instructions from the extracellular matrix.
Matrix biology : journal of the International Society for Matrix Biology
Schaefer L, Dikic I PubMed
Jun 2021 Volume: 100-101 Issue: Pages: 1-8

Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection.
The Journal of biological chemistry
Mukherjee R, Bhattacharya A, Bojkova D, Mehdipour AR, Shin D, Khan KS, Hei-Yin Cheung H, Wong KB, Ng WL, Cinatl J, Geurink PP, van der Heden van Noort GJ, Rajalingam K, Ciesek S, Hummer G, Dikic I PubMed
Aug 2021 Volume: 297 Issue: 2 Pages: 100925

Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir.
ACS central science
Lo HS, Hui KPY, Lai HM, He X, Khan KS, Kaur S, Huang J, Li Z, Chan AKN, Cheung HH, Ng KC, Ho JCW, Chen YW, Ma B, Cheung PM, Shin D, Wang K, Lee MH, Selisko B, Eydoux C, Guillemot JC, Canard B, Wu KP, Liang PH, Dikic I, Zuo Z, Chan FKL, Hui DSC, Mok VCT, Wong KB, Mok CKP, Ko H, Aik WS, Chan MCW, Ng WL PubMed
May 2021 Volume: 7 Issue: 5 Pages: 792-802

SIK2 orchestrates actin-dependent host response upon infection.
Proceedings of the National Academy of Sciences of the United States of America
Hahn M, Covarrubias-Pinto A, Herhaus L, Satpathy S, Klann K, Boyle KB, Münch C, Rajalingam K, Randow F, Choudhary C, Dikic I PubMed
May 2021 Volume: 118 Issue: 19 Pages:

Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation.
Cell chemical biology
Kannt A, Đikić I PubMed
Jul 2021 Volume: 28 Issue: 7 Pages: 1014-1031

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Autophagy
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Al... PubMed
Jan 2021 Volume: 17 Issue: 1 Pages: 1-382

Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii.
Scientific reports
Tiku V, Kofoed EM, Yan D, Kang J, Xu M, Reichelt M, Dikic I, Tan MW PubMed
Jan 2021 Volume: 11 Issue: 1 Pages: 618

The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification.
International journal of molecular sciences
Wells CI, Al-Ali H, Andrews DM, Asquith CRM, Axtman AD, Dikic I, Ebner D, Ettmayer P, Fischer C, Frederiksen M, Futrell RE, Gray NS, Hatch SB, Knapp S, Lücking U, Michaelides M, Mills CE, Müller S, Owen D, Picado A, Saikatendu KS, Schröder M, Stolz A, Tellechea M, Turunen BJ, Vilar S, Wang J, Zuercher WJ, Willson TM, Drewry DH PubMed
Jan 2021 Volume: 22 Issue: 2 Pages:

Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection.
Chemistry (Weinheim an der Bergstrasse, Germany)
Kim RQ, Misra M, Gonzalez A, Tomašković I, Shin D, Schindelin H, Filippov DV, Ovaa H, Đikić I, van der Heden van Noort GJ PubMed
Feb 2021 Volume: 27 Issue: 7 Pages: 2506-2512

Tax1BP1 limits hepatic inflammation and reduces experimental hepatocarcinogenesis.
Scientific reports
Waidmann O, Pleli T, Weigert A, Imelmann E, Kakoschky B, Schmithals C, Döring C, Frank M, Longerich T, Köberle V, Hansmann ML, Brüne B, Zeuzem S, Piiper A, Dikic I PubMed
Oct 2020 Volume: 10 Issue: 1 Pages: 16264

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
Nature
Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van der Heden van Noort GJ, Ovaa H, Müller S, Knobeloch KP, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S, Dikic I PubMed
Nov 2020 Volume: 587 Issue: 7835 Pages: 657-662

Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms.
Cell chemical biology
Maculins T, Garcia-Pardo J, Skenderovic A, Gebel J, Putyrski M, Vorobyov A, Busse P, Varga G, Kuzikov M, Zaliani A, Rahighi S, Schaeffer V, Parnham MJ, Sidhu SS, Ernst A, Dötsch V, Akutsu M, Dikic I PubMed
Nov 2020 Volume: 27 Issue: 11 Pages: 1441-1451.e7

MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B.
The EMBO journal
Cinque L, De Leonibus C, Iavazzo M, Krahmer N, Intartaglia D, Salierno FG, De Cegli R, Di Malta C, Svelto M, Lanzara C, Maddaluno M, Wanderlingh LG, Huebner AK, Cesana M, Bonn F, Polishchuk E, Hübner CA, Conte I, Dikic I, Mann M, Ballabio A, Sacco F, Grumati P, Settembre C PubMed
Sep 2020 Volume: 39 Issue: 17 Pages: e105696

Synthesis of Stable NAD Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC.
Chembiochem : a European journal of chemical biology
Madern JM, Kim RQ, Misra M, Dikic I, Zhang Y, Ovaa H, Codée JDC, Filippov DV, van der Heden van Noort GJ PubMed
Oct 2020 Volume: 21 Issue: 20 Pages: 2903-2907

Wss1 Promotes Replication Stress Tolerance by Degrading Histones.
Cell reports
Maddi K, Sam DK, Bonn F, Prgomet S, Tulowetzke E, Akutsu M, Lopez-Mosqueda J, Dikic I PubMed
Mar 2020 Volume: 30 Issue: 9 Pages: 3117-3126.e4

Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB.
Molecular cell
Shin D, Mukherjee R, Liu Y, Gonzalez A, Bonn F, Liu Y, Rogov VV, Heinz M, Stolz A, Hummer G, Dötsch V, Luo ZQ, Bhogaraju S, Dikic I PubMed
Jan 2020 Volume: 77 Issue: 1 Pages: 164-179.e6

TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease.
EMBO reports
Herhaus L, Bhaskara RM, Lystad AH, Gestal-Mato U, Covarrubias-Pinto A, Bonn F, Simonsen A, Hummer G, Dikic I PubMed
Jan 2020 Volume: 21 Issue: 1 Pages: e48317

ER-phagy and human diseases.
Cell death and differentiation
Hübner CA, Dikic I PubMed
Mar 2020 Volume: 27 Issue: 3 Pages: 833-842

Inhibition of bacterial ubiquitin ligases by SidJ-calmodulin catalysed glutamylation.
Nature
Bhogaraju S, Bonn F, Mukherjee R, Adams M, Pfleiderer MM, Galej WP, Matkovic V, Lopez-Mosqueda J, Kalayil S, Shin D, Dikic I PubMed
Aug 2019 Volume: 572 Issue: 7769 Pages: 382-386

Curvature induction and membrane remodeling by FAM134B reticulon homology domain assist selective ER-phagy.
Nature communications
Bhaskara RM, Grumati P, Garcia-Pardo J, Kalayil S, Covarrubias-Pinto A, Chen W, Kudryashev M, Dikic I, Hummer G PubMed
May 2019 Volume: 10 Issue: 1 Pages: 2370

Arsenic Trioxide and (-)-Gossypol Synergistically Target Glioma Stem-Like Cells via Inhibition of Hedgehog and Notch Signaling.
Cancers
Linder B, Wehle A, Hehlgans S, Bonn F, Dikic I, Rödel F, Seifert V, Kögel D PubMed
Mar 2019 Volume: 11 Issue: 3 Pages:

ER-phagy at a glance.
Journal of cell science
Grumati P, Dikic I, Stolz A PubMed
Sep 2018 Volume: 131 Issue: 17 Pages:

Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination.
Nature
Kalayil S, Bhogaraju S, Bonn F, Shin D, Liu Y, Gan N, Basquin J, Grumati P, Luo ZQ, Dikic I PubMed
May 2018 Volume: 557 Issue: 7707 Pages: 734-738

Ubiquitin signaling and autophagy.
The Journal of biological chemistry
Grumati P, Dikic I PubMed
Apr 2018 Volume: 293 Issue: 15 Pages: 5404-5413

Maternal prolactin during late pregnancy is important in generating nurturing behavior in the offspring.
Proceedings of the National Academy of Sciences of the United States of America
Sairenji TJ, Ikezawa J, Kaneko R, Masuda S, Uchida K, Takanashi Y, Masuda H, Sairenji T, Amano I, Takatsuru Y, Sayama K, Haglund K, Dikic I, Koibuchi N, Shimokawa N PubMed
Dec 2017 Volume: 114 Issue: 49 Pages: 13042-13047

Manatee invariants reveal functional pathways in signaling networks.
BMC systems biology
Amstein L, Ackermann J, Scheidel J, Fulda S, Dikic I, Koch I PubMed
Jul 2017 Volume: 11 Issue: 1 Pages: 72

Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy.
eLife
Grumati P, Morozzi G, Hölper S, Mari M, Harwardt MI, Yan R, Müller S, Reggiori F, Heilemann M, Dikic I PubMed
Jun 2017 Volume: 6 Issue: Pages:

Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins.
Scientific reports
Rogov VV, Suzuki H, Marinković M, Lang V, Kato R, Kawasaki M, Buljubašić M, Šprung M, Rogova N, Wakatsuki S, Hamacher-Brady A, Dötsch V, Dikic I, Brady NR, Novak I PubMed
Apr 2017 Volume: 7 Issue: 1 Pages: 1131

Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator.
eLife
Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch AK, Müller S, Dikic I, Mittelbronn M, Behrends C PubMed
Feb 2017 Volume: 6 Issue: Pages:

In Silico Knockout Studies of Xenophagic Capturing of Salmonella.
PLoS computational biology
Scheidel J, Amstein L, Ackermann J, Dikic I, Koch I PubMed
Dec 2016 Volume: 12 Issue: 12 Pages: e1005200

SPRTN is a mammalian DNA-binding metalloprotease that resolves DNA-protein crosslinks.
eLife
Lopez-Mosqueda J, Maddi K, Prgomet S, Kalayil S, Marinovic-Terzic I, Terzic J, Dikic I PubMed
Nov 2016 Volume: 5 Issue: Pages:

How the proteasome is degraded.
Proceedings of the National Academy of Sciences of the United States of America
Hoeller D, Dikic I PubMed
Nov 2016 Volume: 113 Issue: 47 Pages: 13266-13268

Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria.
Proceedings of the National Academy of Sciences of the United States of America
Richter B, Sliter DA, Herhaus L, Stolz A, Wang C, Beli P, Zaffagnini G, Wild P, Martens S, Wagner SA, Youle RJ, Dikic I PubMed
Apr 2016 Volume: 113 Issue: 15 Pages: 4039-44

Binding of SGTA to Rpn13 selectively modulates protein quality control.
Journal of cell science
Leznicki P, Korac-Prlic J, Kliza K, Husnjak K, Nyathi Y, Dikic I, High S PubMed
Sep 2015 Volume: 128 Issue: 17 Pages: 3187-96

Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis.
eLife
Kumari S, Redouane Y, Lopez-Mosqueda J, Shiraishi R, Romanowska M, Lutzmayer S, Kuiper J, Martinez C, Dikic I, Pasparakis M, Ikeda F PubMed
Dec 2014 Volume: 3 Issue: Pages:

Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features.
Nature genetics
Lessel D, Vaz B, Halder S, Lockhart PJ, Marinovic-Terzic I, Lopez-Mosqueda J, Philipp M, Sim JC, Smith KR, Oehler J, Cabrera E, Freire R, Pope K, Nahid A, Norris F, Leventer RJ, Delatycki MB, Barbi G, von Ameln S, Högel J, Degoricija M, Fertig R, Burkhalter MD, Hofmann K, Thiele H, Altmüller J, Nürnberg G, Nürnberg P, Bahlo M, Martin GM, Aalfs CM, Oshima J, Terzic J, Amor DJ, Dikic I, Ramadan K, Kubisch C PubMed
Nov 2014 Volume: 46 Issue: 11 Pages: 1239-44

Breaking the limits of artificial ubiquitination.
Proceedings of the National Academy of Sciences of the United States of America
Putyrski M, Dikic I PubMed
Oct 2013 Volume: 110 Issue: 44 Pages: 17606-7

Parkin promotes cell survival via linear ubiquitination.
The EMBO journal
Fiškin E, Dikic I PubMed
Apr 2013 Volume: 32 Issue: 8 Pages: 1072-4

A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7.
The EMBO journal
Verhelst K, Carpentier I, Kreike M, Meloni L, Verstrepen L, Kensche T, Dikic I, Beyaert R PubMed
Oct 2012 Volume: 31 Issue: 19 Pages: 3845-55

Fighting mycobacteria through ISGylation.
EMBO reports
Pohl C, Dikic I PubMed
Oct 2012 Volume: 13 Issue: 10 Pages: 872-3

Signalling through the grapevine.
EMBO reports
Dikic I, Daly RJ PubMed
Mar 2012 Volume: 13 Issue: 3 Pages: 178-80

Healthy ageing through regulated proteostasis.
The EMBO journal
Rajalingam K, Dikic I PubMed
Aug 2011 Volume: 30 Issue: 15 Pages: 2983-5

Spatial organization of transmembrane receptor signalling.
The EMBO journal
Bethani I, Skånland SS, Dikic I, Acker-Palmer A PubMed
Aug 2010 Volume: 29 Issue: 16 Pages: 2677-88

CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice.
The EMBO journal
Shimokawa N, Haglund K, Hölter SM, Grabbe C, Kirkin V, Koibuchi N, Schultz C, Rozman J, Hoeller D, Qiu CH, Londoño MB, Ikezawa J, Jedlicka P, Stein B, Schwarzacher SW, Wolfer DP, Ehrhardt N, Heuchel R, Nezis I, Brech A, Schmidt MHH, Fuchs H, Gailus-Durner V, Klingenspor M, Bogler O, Wurst W, Deller T, de Angelis MH, Dikic I PubMed
Jul 2010 Volume: 29 Issue: 14 Pages: 2421-32

The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation.
Proceedings of the National Academy of Sciences of the United States of America
Vivanco I, Rohle D, Versele M, Iwanami A, Kuga D, Oldrini B, Tanaka K, Dang J, Kubek S, Palaskas N, Hsueh T, Evans M, Mulholland D, Wolle D, Rajasekaran S, Rajasekaran A, Liau LM, Cloughesy TF, Dikic I, Brennan C, Wu H, Mischel PS, Perera T, Mellinghoff IK PubMed
Apr 2010 Volume: 107 Issue: 14 Pages: 6459-64

Nix is a selective autophagy receptor for mitochondrial clearance.
EMBO reports
Novak I, Kirkin V, McEwan DG, Zhang J, Wild P, Rozenknop A, Rogov V, Löhr F, Popovic D, Occhipinti A, Reichert AS, Terzic J, Dötsch V, Ney PA, Dikic I PubMed
Jan 2010 Volume: 11 Issue: 1 Pages: 45-51

The ataxia (axJ) mutation causes abnormal GABAA receptor turnover in mice.
PLoS genetics
Lappe-Siefke C, Loebrich S, Hevers W, Waidmann OB, Schweizer M, Fehr S, Fritschy JM, Dikic I, Eilers J, Wilson SM, Kneussel M PubMed
Sep 2009 Volume: 5 Issue: 9 Pages: e1000631

Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization.
Proceedings of the National Academy of Sciences of the United States of America
Sabbioneda S, Green CM, Bienko M, Kannouche P, Dikic I, Lehmann AR PubMed
Feb 2009 Volume: 106 Issue: 8 Pages: E20; author reply E21

Signal processing by its coil zipper domain activates IKK gamma.
Proceedings of the National Academy of Sciences of the United States of America
Bloor S, Ryzhakov G, Wagner S, Butler PJ, Smith DL, Krumbach R, Dikic I, Randow F PubMed
Jan 2008 Volume: 105 Issue: 4 Pages: 1279-84