Research Groups

 

Publications of Martin Vabulas (Results: 22)

 

Recognition of enzymes lacking bound cofactor by protein quality control.
Proceedings of the National Academy of Sciences of the United States of America
Martínez-Limón A, Alriquet M, Lang WH, Calloni G, Wittig I, Vabulas RM PubMed
Oct 2016 Volume: 113 Issue: 43 Pages: 12156-12161

Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response.
Molecular & cellular proteomics : MCP
Sharma K, Vabulas RM, Macek B, Pinkert S, Cox J, Mann M, Hartl FU PubMed
Mar 2012 Volume: 11 Issue: 3 Pages: M111.014654

Aberrant protein interactions in amyloid disease.
Cell cycle (Georgetown, Tex.)
Vabulas RM, Hartl FU PubMed
May 2011 Volume: 10 Issue: 10 Pages: 1512-3

The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication.
The EMBO journal
Resenberger UK, Harmeier A, Woerner AC, Goodman JL, Müller V, Krishnan R, Vabulas RM, Kretzschmar HA, Lindquist S, Hartl FU, Multhaup G, Winklhofer KF, Tatzelt J PubMed
May 2011 Volume: 30 Issue: 10 Pages: 2057-70

Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions.
Cell
Olzscha H, Schermann SM, Woerner AC, Pinkert S, Hecht MH, Tartaglia GG, Vendruscolo M, Hayer-Hartl M, Hartl FU, Vabulas RM PubMed
Jan 2011 Volume: 144 Issue: 1 Pages: 67-78

Protein folding in the cytoplasm and the heat shock response.
Cold Spring Harbor perspectives in biology
Vabulas RM, Raychaudhuri S, Hayer-Hartl M, Hartl FU PubMed
Dec 2010 Volume: 2 Issue: 12 Pages: a004390

Proteasome function and protein biosynthesis.
Current opinion in clinical nutrition and metabolic care
Vabulas RM PubMed
Jan 2007 Volume: 10 Issue: 1 Pages: 24-31

A balance of protein synthesis and proteasome-dependent degradation determines the maintenance of LTP.
Neuron
Fonseca R, Vabulas RM, Hartl FU, Bonhoeffer T, Nägerl UV PubMed
Oct 2006 Volume: 52 Issue: 2 Pages: 239-45

Protein synthesis upon acute nutrient restriction relies on proteasome function.
Science (New York, N.Y.)
Vabulas RM, Hartl FU PubMed
Dec 2005 Volume: 310 Issue: 5756 Pages: 1960-3

Heat shock proteins as ligands of toll-like receptors.
Current topics in microbiology and immunology
Vabulas RM, Wagner H, Schild H PubMed
2002 Volume: 270 Issue: Pages: 169-84

Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Journal of immunology (Baltimore, Md. : 1950)
Weighardt H, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B PubMed
Sep 2002 Volume: 169 Issue: 6 Pages: 2823-7

CpG-DNA aided cross-presentation of soluble antigens by dendritic cells.
European journal of immunology
Maurer T, Heit A, Hochrein H, Ampenberger F, O'Keeffe M, Bauer S, Lipford GB, Vabulas RM, Wagner H PubMed
Aug 2002 Volume: 32 Issue: 8 Pages: 2356-64

Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments.
European journal of immunology
Ahmad-Nejad P, Häcker H, Rutz M, Bauer S, Vabulas RM, Wagner H PubMed
Jul 2002 Volume: 32 Issue: 7 Pages: 1958-68

The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway.
The Journal of biological chemistry
Vabulas RM, Braedel S, Hilf N, Singh-Jasuja H, Herter S, Ahmad-Nejad P, Kirschning CJ, Da Costa C, Rammensee HG, Wagner H, Schild H PubMed
Jun 2002 Volume: 277 Issue: 23 Pages: 20847-53

HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway.
The Journal of biological chemistry
Vabulas RM, Ahmad-Nejad P, Ghose S, Kirschning CJ, Issels RD, Wagner H PubMed
Apr 2002 Volume: 277 Issue: 17 Pages: 15107-12

Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells.
The Journal of biological chemistry
Vabulas RM, Ahmad-Nejad P, da Costa C, Miethke T, Kirschning CJ, Häcker H, Wagner H PubMed
Aug 2001 Volume: 276 Issue: 33 Pages: 31332-9

Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins.
European journal of immunology
Sparwasser T, Vabulas RM, Villmow B, Lipford GB, Wagner H PubMed
Dec 2000 Volume: 30 Issue: 12 Pages: 3591-7

Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6.
The Journal of experimental medicine
Häcker H, Vabulas RM, Takeuchi O, Hoshino K, Akira S, Wagner H PubMed
Aug 2000 Volume: 192 Issue: 4 Pages: 595-600

CpG-DNA activates in vivo T cell epitope presenting dendritic cells to trigger protective antiviral cytotoxic T cell responses.
Journal of immunology (Baltimore, Md. : 1950)
Vabulas RM, Pircher H, Lipford GB, Häcker H, Wagner H PubMed
Mar 2000 Volume: 164 Issue: 5 Pages: 2372-8

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells.
European journal of immunology
Sparwasser T, Koch ES, Vabulas RM, Heeg K, Lipford GB, Ellwart JW, Wagner H PubMed
Jun 1998 Volume: 28 Issue: 6 Pages: 2045-54

Rapid clearance of the bacterial superantigen staphylococcal enterotoxin B in vivo.
Infection and immunity
Vabulas R, Bittlingmaier R, Heeg K, Wagner H, Miethke T PubMed
Nov 1996 Volume: 64 Issue: 11 Pages: 4567-73

Mechanisms of peripheral T cell deletion: anergized T cells are Fas resistant but undergo proliferation-associated apoptosis.
European journal of immunology
Miethke T, Vabulas R, Bittlingmaier R, Heeg K, Wagner H PubMed
Jul 1996 Volume: 26 Issue: 7 Pages: 1459-67