Member of Molecular Cell Biology of Plants Group
Prof. Dr. Enrico Schleiff
Professor & group leader
Phone: +49 (0)69 798-29287
Fax: +49 (0)69 798-29286
schleiff(at)bio.uni-frankfurt.de
Website
| Curriculum Vitae | |
| Since 2019 | Director, Frankfurt Institute for Advanced Studies |
| 2014-2019 | Director, Buchmann Institute of Molecular Life Sciences |
| Since 2013 | Liaison Officer of "Studienstiftung des Deutschen Volkes" |
| 2012-2018 | Vice president, Goethe University Frankfurt |
| 2012-2019 | Member of the Board of Directors, Cluster of Excellence Macromolecular Complexes |
| Since 2012 | Chair of "SPOT-ITN", funded by the Marie Curie EU-programm |
| Since 2012 | Co-Director of UniWIND |
| Since 2011 | Vice chair, SFB 902 |
| 2009 - 2012 | Director, Center of Membrane Proteomics, Frankfurt |
| 2007-2019 | PI, Cluster of Excellence "Macromolecular Complexes" |
| Since 2007 | Professor (W3) at Goethe University, Frankfurt, Head of the Institute for "Molecular Cell Biology of Plants" |
| 2003 - 2007 | Independent young investigator group leader at the LMU Munich, funded by VW-Foundation |
| 1999 - 2003 | Postdoc position at University of Kiel / LMU Munich; mentor: J. Soll |
| 1993 - 1994 | Laboratory work at the GU Mainz; Mentor: Prof Otten |
| 1999 | Laboratory work at the TU Dresden; mentor: Dr Märten |
| University education | |
| 2003 | Habilitation in Cell-Biology/ Botany at the LMU Munich |
| 1999 | PhD Examination |
| 1996 - 1998 | PhD, McGill University Montreal, Canada, (exceptional; mentor: G.C. Shore) |
| 1995 | Master thesis, Biocenter of the University Basel, Switzerland (very good; mentor: Prof Schwarz / Dr Vergeres) |
| 1992 - 1995 | Diploma in Physics, Gutenberg University of Mainz (very good) |
| 1992 | Bachelor/Prediploma, Physics, Charles-University of Prague, Czech Republik |
| 1990 - 1992 | Study of Physics, Charles-University of Prague, Czech Republik |
| Fellowships & Awards | |
| 2014 | Spiridon Brusina Medal from the Croatian Society for Biochemistry and Molecular Biology |
| 2004 | Strassburger Prize |
| 2004 | Habilitationspreis of the LMU Munich |
| 2003 - 2008 | Volkswagen-Nachwuchsgruppenleiter (Deutschland) |
| 1999 | Entrance into the Book of honor McGill University |
| 1998 | McGill Cancer Center Award, Canada |
| 1998 | McGill Major PhD Award, Canada |
| 1997 | Alma Mater Award, McGill University, Canada |
| 1997 | McKinnell Award (Canada) |
| 1996 - 1998 | DAAD HSP-II & HSP-III Fellowship |
| 1995 | Fellowship from the Nikolaus & Berta Burckhardt-Bürgin foundation, Switzerland |
| 1995 | Fellowship of the Dr Carl Duisberg foundation |
Research interests
Protein targeting and translocation to and across membranes
GTPase function
Protein and organelle evolution
Metabolite transport and transporters
Stress response mechanisms in plants
Ribosome biogenesis
Bioinformatic analysis and modeling of protein structures
Five most important publications 2011-2015
Tillmann B, Röth S, Bublak D, Sommer M, Stelzer E, Scharf K-D, Schleiff E (2015) Hsp90 is involved in the regulation of cytosolic precursor protein abundance in tomato. Mol Plant 8:228-241
Lumme C, Altan-Martin H, Dastvan R, Sommer MS, Oreb M, Schuetz D, Hellenkamp B, Mirus O, Kretschmer J, Lyubenova S, Kügel W, Medelnik JP, Dehmer M, Michaelis J, Prisner TF, Hugel T, Schleiff E (2014) Nucleotides and substrates trigger the dynamics of the Toc34 GTPase homodimer involved in chloroplast preprotein translocation. Structure 22:526-538
Hellmich UA, Weis BL, Lioutikov A, Wurm JP, Kaiser M, Christ NA, Hantke K, Kotter P, Entian KD, Schleiff E*, Wöhnert J* (2013) Essential ribosome assembly factor Fap7 regulates a hierarchy of RNA-protein interactions during small ribosomal subunit biogenesis. P Natl Acad Sci USA 110:15253-15258
Tripp J, Hahn A, Koenig P, Flinner N, Bublak D, Brouwer EM, Ertel F, Mirus O, Sinning I, Tews I, Schleiff E (2012) Structure and conservation of the periplasmic targeting factor Tic22 protein from plants and cyanobacteria. J Biol Chem 287:24164-24173
Hahn A, Bublak D, Schleiff E, Scharf KD (2011) Crosstalk between Hsp90 and Hsp70 chaperones and heat stress transcription factors in tomato. Plant Cell 23:741-755
*joint corresponding authors
Ivonne WogatzkeAdministrative Assistant
Phone: +49 (0)69 798-29285
Fax: +49 (0)69 798-29286
wogatzke(at)bio.uni-frankfurt.de